Final Programme
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SUNDAY 13 SEPTEMBER
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16:30 – 18:30 OPENING & PLENARY SESSION 1: ESOT Meets the World LIVE CASTED
16:30 – 16:45 Welcome addresses by the Congress Chairs:
Jan Lerut, Brussels, Belgium;
Dirk van Raemdonck, Leuven, Belgium
16:45 – 18:00 ESOT MEETS THE WORLD
KEY LEARNING: OVERVIEW OF TX IN CULTURALLY DIVERSE REGIONS
GENERAL AUDIENCE – DONATION POLICIES – POLITICS – CULTURAL ISSUES
Moderator: John Forsythe, ESOT President
Forum on major issues on Transplantation:
- Basic science challenges in transplantation today
- Clinical issues that need to be overcome in solid organ transplantation
- The answer to deceased donor donation; increasing the levels
- Living donation, ethically unjustified or the golden answer?
- The next big thing in Transplantation
- In ten years...
Discussants:
- The American Society of Transplantation (AST)
Roslyn Mannon, Birmingham, United States - The Asian Society of Transplantation (AST)
Chao-Long Chen, Taipei, Taiwan - The Middle East Society of Transplantation (MESOT)
Seyed Ali Malek-Hosseini, Shiraz, Iran - The South Latin American & Caribbean Society of Transplantation (STALYC)
Valter Duro Garcia, Porto Alegre, Brasil
18:00 – 18:20 Keynote presentation: Building a more Social Europe, One Step at a Time
Herman van Rompuy, President Emeritus of the European Council
18:20 – 18:45 PIANO PERFORMANCE by Enrica Ciccarelli and Edoardo Zosi
19:00 – 20:00 ePoster ‘Speed Dating’ Session Opening
19:00 – 22:00 Networking evening: A night at the Square
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MONDAY 14 SEPTEMBER
09:10 – 10:40 STATE OF THE ART 1: Global warming in transplantation LIVE CASTED
SURGEONS&COORDINATORS - INCREASING THE ORGAN POOL QUALITY AND QUANTITY
Chairs: Diethard Monbaliu, Leuven, Belgium
Benoit Barrou, Paris, France
09:10 Cool is beautiful
Philipp Dutkowski, Zurich, Switzerland
09:30 Can we escape global warming?
Gabriel Oniscu, Edinburgh, United Kingdom
09:50 Keeping the heart warm and the lungs breathing
Martin Strueber, Grand Rapids, United States
10:10 The down of the new ice age
Korkut Uygun, Boston, United States
10:30 Q&A
09:10 – 10:40 STATE OF THE ART 2: B-yond the horizon: humoral responses in transplantation
Chairs: Menna Clatworthy, Cambridge, United Kingdom
Birgit Sawitzki, Berlin, Germany
09:10 Humoral responses: basic concepts in cinemascope!
Facundo Batista, London, United Kingdom
09:30 Detection and clinical relevance of donor specific antibodies
Frans Claas, Leiden, Netherlands
09:50 Antibody-independent functions of B cells in allograft rejection
Geetha Chalasani, Pittsburgh, United States
10:10 B cells not always the bad guys: B cell regulatory functions
Sophie Brouard, Nantes, France
10:30 Q&A
09:10 – 10:40 STATE OF THE ART 3: Decision tree or lottery: allocating grafts and therapies
Chairs: Roslyn Mannon, Birmingham, United States
Luuk Hilbrands, Nijmegen, The Netherlands
09:10 Tailor made organ allocation
Axel Rahmel, DSO, Germany
09:30 Tailor made surgery
Peter Friend, Oxford, United Kingdom
09:50 Tailor made immunosuppression
Teun van Gelder, Rotterdam, The Netherlands
10:10 Tailor made post transplant follow up?
Bryce Kiberd, Halifax, Canada
10:40 – 11:10 Coffee Break
11:10 – 12:40 SPECIAL FOCUS SESSION: The Devil's Advocate
Contradictory discussion of clinical trials
Chairs: Thierry Berney, Geneva, Switzerland
Luciano Potena, Bologna, Italy
Case 1. Is Liver Transplantation an Option in Colorectal Cancer Patients with Nonresectable Liver Metastases and Progression on All Lines of Standard Chemotherapy?
Ann Surg Oncol. 2014 Oct 9. [Epub ahead of print]. Dueland S, Hagness M, Line PD, Guren TK, Tveit KM, Foss A.
11:10 Defender: Aksel Foss, Oslo, Norway
11:20 Opponent: François-René Pruvot, Lille, France
11:30 Discussion
Case 2. Everolimus initiation and early calcineurin inhibitor withdrawal in heart transplant recipients: a randomized trial.
Am J Transplant. 2014 Aug. Andreassen AK, Andersson B, Gustafsson F, Eiskjaer H, Radegran G, Gude E, Jansson, K, Solbu D, Sigurdardottir V, Arora S, Dellgren G, Gullestad L.
11:40 Defender: Arne Andreassen, Oslo, Norway
11:50 Opponent: Luciano Potena, Bologna, Italy
12:00 Discussion
Case 3. Gestational hypertension and preeclampsia in living kidney donors.
N Engl J Med. 2015 Jan 8; Garg AX, Nevis IF, McArthur E, Sontrop JM, Koval JJ, Lam NN, Hildebrand AM, Reese PP, Storsley L, Gill JS, Segev DL, Habbous S, Bugeja A, Knoll GA, Dipchand C, Monroy-Cuadros M, Lentine KL; DONOR Network.
12:10 Defender: Amit Garg, London (Ontario), Canada
12:20 Opponent: Frank Dor, Rotterdam, The Netherlands
12:30 Discussion
13:00 – 14:00 Lunch Break
13:00 – 14:00 Future Leaders Forum by YPT (Young Professionals in Transplantation)
Introduced by: Murat Dayangac, Istanbul, Turkey
Annemarie Weissenbacher, Innsbruck, Austria
Chairs: Dorry Segev, Baltimore, United States
Stefan Schneeberger, Innsbruck, Austria
Forum with representatives from:
- ILTS Vanguard Group: Burcin Ekser, Indianapolis, United States
- ASTS Vanguard Group: Mike Englesbe, Ann Arbor, United States
- ESOT: Antje Habicht, Munich, Germany
- British Transplantation Society: Bynvant Sandhu, London, United Kingdom
- Should I stay or should I go?
Is it more useful to stay in one institution throughout your education, or is it more advisable to complete fellowships abroad, changing institution to gain a broader experience? How do you get to the top? Organizing your own career with "center hopping" or rather staying in one place and "grow up" in the same team? - To specialize or not to specialize?
Recognized specializations in transplant surgery and medicine are not available in all countries. Should you narrow your education down to become a specialist in transplantation or is a broader education in general surgery/hepatology/nephrology a better bet.
14:05 – 15:30 PLENARY SESSION 2: Of men and machine LIVE CASTED
GENERAL INTEREST – ARTIFICIAL ORGANS
Chairs: Thierry Berney, Geneva, Switzerland
Gabriel Oniscu, Edinburgh, United Kingdom
14:05 Ethics & the Robot: Updating Asimov
Liam Plant, Cork, Ireland
14:25 Printing the human body
John D Jackson, Winston-Salem, United States
14:45 Artificial organs: a step towards the bionic man?
Shuvo Roy, San Francisco, United States
15:05 Keynote presentation II: I, Cyborg!
Kevin Warwick, Coventry, United Kingdom
15:35 – 16:00 Coffee Break
16:00 – 17:00 BEYOND THE HORIZON 1: The future of the human body LIVE CASTED
GENERAL AUDIENCE NOBODY REALLY SPECIALIZED - UNUSUAL TRANSPLANT AND NOVELTY
Chairs: Franco Citterio, Rome, Italy
Andreas Pascher, Berlin, Germany
16:00 Giving Birth to Uterus Transplantation
Mats Brännström, Gothenburg, Sweden
16:20 Neural stem cells for spinal cord repair – Ready to walk the talk?
Norbert Weidner, Heidelberg, Germany
16:40 Changing the face of transplantation
Stephen Bartlett, Baltimore, United States
16:00 – 17:00 BEYOND THE HORIZON 2: The race of tolerance with regenerative medicine
Chairs: Alain Le Moine, Brussels, Belgium
Thomas Wekerle, Vienna, Austria
16:00 The Odyssey of tolerance induction in solid organ transplantation
Herman Waldmann, Oxford, United Kingdom
16:20 The promises of regenerative medicine
Harold Ott, Boston, United States
16:40 Racing against or complementing each other?
Sam Strober, Palo Alto, United States
17:00 – 18:00 ESOT meets the Editors
Round table and interactive session with questions from the floor to discuss issues related to medical journal publication:
- Impact factor: how is it calculated?
- Reviewing process
- Submitters’ choice and common mistakes
Moderator: Philip Halloran, Edmonton, Canada
Editors from major medical journals present and answer questions from the audience:
- American Journal of Transplantation (AJT): Sandy Feng, San Francisco, United States, Deputy Editor
John O’Grady, London, United Kingdom, Deputy Editor - Transplant International (TI): Thomas Wekerle, Vienna, Austria, Editor-in-Chief
- Transplantation Direct: Edward Geissler, Regensburg, Germany, Executive Editor
- Transplantation: Carla Baan, Rotterdam, The Netherlands, Editor
- PLoS One: Lorna Marson, Edinburgh, United Kingdom; Academic Editor
17:00 – 18:00 HOTT Project Workshop - Organ trafficking anno 2015: the latest insights
Chairs: Jan Lerut, Brussels, Belgium
Willem Weimar, Rotterdam, The Netherlands
17:00 Revealing the modus operandi of organ trafficking networks
Martin Gunnarson, Lund, Sweden
17:20 Tackling organ trafficking: a prosecutor’s perspective
Jonathan Ratel, Pristina, Kosovo
17:40 Transplant professionals should breach their secrecy oath
Frederike Ambagtsheer, Rotterdam, The Netherlands
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TUESDAY 15 SEPTEMBER
09:10 – 10:40 STATE OF THE ART 4: Markers and makers of success and failure LIVE CASTED
PHYSICIANS AND TRANSLATIONAL RESEARCHERS - PERSONALIZED MEDICINE
Chairs: Minnie Sarwal, San Francisco, United States
Alberto Sanchez Fueyo, London, United Kingdom
09:10 Personalized medicine and precision medicine in solid organ transplantation
Alexandre Loupy, Paris, France
09:30 Drinking from the fire hose– a critical appraisal of biomarkers in transplantation
Rainer Oberbauer, Vienna, Austria
09:50 Facing the hurdles to clinical implementation of novel biomarkers
Hans-Dieter Volk, Berlin, Germany
10:10 Biomarker implementation in clinical practice: the regulatory agency's perspective
Thorsten Vetter, EMA London, United Kingdom
10:30 Q&A
09:10 – 10:40 STATE OF THE ART 5: The new frontier: transplantation across antibody barriers
Chairs: Frans Claas, Leiden, Netherlands
Denis Glotz, Paris, France
09:10 Squaring the circle: Hybridizing desensitization with paired exchange
Bob Montgomery, Baltimore, United States
09:30 Acceptable mismatches, past and future
Sebastian Heidt, Leiden,The Netherlands
09:50 ABO incompatible liver transplantation
Gi-Won Song, Seoul, Korea
10:10 Autoantibodies against the graft, do they mean anything?
Dany Anglicheau, Paris, France
10:30 Q&A
09:10 – 10:40 STATE OF THE ART 6: The enemy within: improving compliance and drug levels
Chairs: Patrizia Burra, Padova, Italy
Teun van Gelder, Rotterdam, The Netherlands
09:10 Intra-patient variability of drug concentrations as a predictor of non-adherence
Dirk Kuypers, Leuven, Belgium
09:30 Risk factors of poor adherence, prevention and education in adult
Giacomo Germani, Padova, Italy
09:50 New tools to detect non-adherence
Sabina de Geest, Basel, Switzerland
10:10 The journey from adolescence to adulthood
Paul Harden, Oxford, United Kingdom
10:30 Q&A
10:40 – 11:10 Coffee Break
11:10 – 12:40 SPECIAL FOCUS SESSION: The Devil's Advocate
Contradictory discussion of Basic Science Studies
Chairs: Alain Le Moine, Brussels, Belgium
Thomas Wekerle, Vienna, Austria
Case 1. G-CSF mobilizes CD34+ regulatory monocytes that inhibit graft-versus-host disease
Maud D’Aveni, Julien Rossignol, Tereza Coman, Shivajanani Sivakumaran, Stephen Henderson, Teresa Manzo, Pedro Santos e Sousa, Julie Bruneau, Guillemette Fouquet, Flora Zavala, Olinda Alegria-Prévot, Meriem Garfa-Traoré, Felipe Suarez, Hélène Trebeden-Nègre, Mohamad Mohty, Clare L. Bennett, Ronjon Chakraverty, Olivier Hermine, and Marie-Thérèse Rubio
11:10 Defender: Olivier Hermine, Paris, France
11:20 Opponent: James Hutchinson, Regensburg, Germany
11:30 Discussion
Case 2. Non-self recognition by monocytes initiates allograft rejection
Martin H. Oberbarnscheidt, Qiang Zeng,Qi Li,Hehua Dai, Amanda L. Williams, Warren D. Shlomchik, David M. Rothstein, and Fadi G. Lakkis
11:40 Defender: Fadi Lakkis, Pittsburgh, United States
11:50 Opponent: Herman Waldmann, Oxford, United Kingdom
12:00 Discussion
Case 3. Inhibition of the mTORC Pathway in the Antiphospholipid Syndrome
Guillaume Canaud, M.D., Ph.D., Frank Bienaimé, M.D., Ph.D., Fanny Tabarin, M.S., Guillaume Bataillon, M.D., Danielle Seilhean, M.D., Laure-Hélène Noël, M.D.,Marie-Agnès Dragon-Durey, M.D., Ph.D., Renaud Snanoudj, M.D., Ph.D., Gérard Friedlander, M.D., Ph.D., Lise Halbwachs-Mecarelli, Ph.D., Christophe Legendre, M.D., and Fabiola Terzi, M.D., Ph.D.
12:10 Defender: Guillaume Canaud, Paris, France
12:20 Opponent: Alexandre Hertig, Paris, France
12:30 Discussion
11:10 – 12:40 Guess what? Striking clinical cases by the ESOT Education Committee
Interactive and very instructive session where difficult cases and difficult decisions will be addressed as in a quiz. Win confidence and solve the problem.
Chairs: Patrizia Burra, Padova, Italy
Frank Dor, Rotterdam, The Netherlands
- The ascites that would not go away
John O’Grady, London, United Kingdom
- An extreme case in live donor kidney transplantation - when is it time to stop?
Nizam Mamode, London, United Kingdom
13:00 – 14:00 Lunch Break
13:00 – 14:00 Rising Stars Video Session by YPT
New methods not always become ‘public’, we are going to look for hidden rising stars to make them visible! This session is reserved for innovative projects or methodology that will be presented in a video.
Chair: Dries Braat, Leiden, the Netherlands
13:00 Surgical treatment for chylous ascites after laparoscopic donor nephrectomy
Mert Altinel, Ankara, Turkey
13:10 Splenic artery transposition for arterial reconstruction in living donor liver transplantation: a perfect substitute
Arzu Oezcelik, Istanbul, Turkey
13:20 Right-sided donor nephrectomy with hand-assisted retroperitoneoscopic approach
offers increased safety with excellent outcome
Soyakan Barlas, Istanbul, Turkey
13:30 Optimized decellularization of rat livers by arterial and portal venous perfusion under oscillating pressure conditions
Karl Hillebrandt, Berlin, Germany
13:40 Sub-normothermic oxygenated machine perfusion ameliorated recipient survival
after mouse liver transplantation using DCD grafts
Masato Fujiyoshi, Hokkaido, Japan
14:05 – 15:30 PLENARY SESSION 3: Transplantation 2.0.15 LIVE CASTED
Chairs: Pietro Cippà, Zurich, Switzerland
Stefan Schneeberger, Innsbruck, Austria
14:05 Social Media and transplantation: an ethical point of view
Adam Peña, Houston, United States
14:25 Age of real-time medicine
Bart Van Den Bosch, Leuven, Belgium
14:45 Will Big Data reshape transplantation?
Dorry Segev, Baltimore, United States
15:05 Keynote presentation III: Reshaping healthcare through eHealth
Lucien Engelen, Nijmegen, The Netherlands
15:35 – 16:00 Coffee Break
16:00 – 17:00 BEYOND THE HORIZON 3: Organ resuscitation lab LIVE CASTED
RECONDITIONING THE ORGANS VERSUS GROWING THE ORGANS - TRANSLATIONAL & PHYSICIAN
Chairs: Dirk van Raemdonck, Leuven, Belgium
Chris Watson, Cambridge, United Kingdom
16:00 Organ reconditioning: the new transplant evolution?
Jacques Pirenne, Leuven, Belgium
16:20 From scaffolds to functioning organs
Andrea Gobin, Houston, United States
16:40 The organ hub – the future model for solid organ transplantation
Shaf Keshavjee, Toronto, Canada
16:00 – 17:00 BEYOND THE HORIZON 4: Crazy transplants or transplants of tomorrow?
Chairs: Gerald Brandacher, Baltimore, United States
Benoit Lengele, Brussels, Belgium
16:00 Vascularized organ xenotransplantation
Robin Pierson, Baltimore, United States
16:20 Growing new organs in vivo
Hiro Nakauchi, San Francisco, United States
16:40 Heart transplantation from non-heart-beating donors
Hendrik Tevaearai, Berne, Switzerland
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WEDNESDAY 16 SEPTEMBER
09:10 – 10:30 STATE OF THE ART 7: Immunosuppression: Is the pipeline empty?
GENERAL PHYSICIANS - HOW TO GET NEW DRUGS IN OUR FIELD
Chairs: Josep Grinyo, Barcelona, Spain
Karl Martin Wissing, Brussels, Belgium
09:10 Promising novel agents: what happened to them?
Klemens Budde, Berlin, Germany
09:30 What are the new immunosuppressive drugs in the pipeline?
Christophe Legendre, Paris, France
09:50 New immunosuppressants: interaction between academia, biopharma and regulatory agencies
Randall Morris, Palo Alto, United States
10:10 Drug repositioning: teaching old drugs new tricks
Yves Moreau, Leuven, Belgium
10:30 Q&A
09:10 – 10:30 STATE OF THE ART 8: Cell therapy: Hit or miss?
Chairs: Edward Geissler, Regensburg, Germany
Andreas Pascher, Berlin, Germany
09:10 Mesenchymal Stem Cells in Organ Transplantation
Carla Baan, Rotterdam, The Netherlands
09:30 Application of suppressive antigen presenting cells in transplantation
James Hutchinson, Regensburg, Germany
09:50 The present status and future of regulatory T cell therapy in organ transplantation
Robert Lechler, London, United Kingdom
10:10 Cell therapy for diabetes
Camillo Ricordi, Miami, United States
10:30 Q&A
09:10 – 10:30 STATE OF THE ART 9: Life after transplantation: blessing or curse?
Chairs: Giacomo Germani, Padova, Italy
Jan Lerut, Brussels, Belgium
09:10 Long-term organ transplant recipient survivors: quality of life
Christiane Kugler, Hannover, Germany
09:30 Sexual function and fertility after solid organ transplant
Patrizia Burra, Padova, Italy
09:50 Pregnancy after solid organ transplant
Corinne Hubinont, Brussels, Belgium
10:10 Physical activity and sports in organ transplant recipients
Alessandro Nanni Costa, Rome, Italy
10:30 Q&A
10:40 – 11:10 Coffee Break
11:00 – 13:00 PLENARY SESSION 4: Beyond the Horizon
Presidential & Honorary Membership
Chairs: John Forsythe, ESOT President
ESOT newly elected President
11:00 Keynote presentation IV: Beyond the Horizon: the astronaut’s view
Jean-Francois Clervoy, European Space Agency
11:20 Beyond the horizon in clinical science
Maarten Naesens, Leuven, Belgium
11:40 Beyond the horizon in basic science
Menna Clatworthy, Cambridge, United Kingdom
12:00 Presidential address
12:15 Jan Lerut celebrating Honorary Member SG Lee, Seoul, South Korea
12:35 Rutger Ploeg celebrating Honorary Member Gerhard Opelz, Heidelberg, Germany
12.55 - 13.00 Closing remarks
ESOT2015 BRUSSELS FINAL PROGRAMME NOW AVAILABLE - PLEASE CLICK HERE TO DOWNLOAD
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